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Chris Drakeley Selected Research

Glucosephosphate Dehydrogenase Deficiency

10/2021Model-based assessment of the safety of community interventions with primaquine in sub-Saharan Africa.
1/2021G6PD Polymorphisms and Hemolysis After Antimalarial Treatment With Low Single-Dose Primaquine: A Pooled Analysis of Six African Clinical Trials.
8/2018Low and heterogeneous prevalence of glucose-6-phosphate dehydrogenase deficiency in different settings in Ethiopia using phenotyping and genotyping approaches.
11/2017Marked variation in prevalence of malaria-protective human genetic polymorphisms across Uganda.
1/2017Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.
8/2015Submicroscopic carriage of Plasmodium falciparum and Plasmodium vivax in a low endemic area in Ethiopia where no parasitaemia was detected by microscopy or rapid diagnostic test.
8/2014Glucose-6-phosphate dehydrogenase status and risk of hemolysis in Plasmodium falciparum-infected African children receiving single-dose primaquine.
2/2014Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: a randomised, controlled, double-blind, dose-ranging trial.
6/2013Tools for mass screening of G6PD deficiency: validation of the WST8/1-methoxy-PMS enzymatic assay in Uganda.
3/2013Study protocol for a randomised controlled double-blinded trial of the dose-dependent efficacy and safety of primaquine for clearance of gametocytes in children with uncomplicated falciparum malaria in Uganda.
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Chris Drakeley Research Topics

Disease

123Malaria
10/2022 - 03/2003
49Infections
01/2022 - 01/2012
22Falciparum Malaria (Plasmodium falciparum Malaria)
01/2022 - 07/2002
12Glucosephosphate Dehydrogenase Deficiency
10/2021 - 05/2009
10Hemolysis
10/2021 - 05/2010
5Anemia
10/2021 - 03/2005
4Fever (Fevers)
11/2021 - 11/2008
4Parasitemia
01/2021 - 01/2015
3Vivax Malaria
01/2022 - 01/2017
2Filarial Elephantiasis (Lymphatic Filariasis)
01/2022 - 05/2013
2Communicable Diseases (Infectious Diseases)
01/2022 - 12/2019
2Bites and Stings (Sting)
07/2021 - 10/2019
2Asymptomatic Infections
01/2020 - 03/2016
2Body Weight (Weight, Body)
01/2017 - 05/2010
1Headache (Headaches)
01/2022
1Cerebral Malaria
10/2020
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
10/2020
1Rabies (Hydrophobia)
01/2019
1Hepatocellular Carcinoma (Hepatoma)
01/2018
1Thalassemia
11/2017
1Hemolytic Anemia
01/2017
1Trachoma
02/2015
1Opportunistic Infections (Opportunistic Infection)
01/2015
1Onchocerciasis
05/2013

Drug/Important Bio-Agent (IBA)

30Antimalarials (Antimalarial Agents)IBA
03/2022 - 04/2003
29AntigensIBA
10/2022 - 01/2009
25AntibodiesIBA
01/2022 - 09/2008
23PrimaquineFDA Link
01/2022 - 05/2010
19artemisinin (artemisinine)IBA
01/2022 - 09/2006
15Pharmaceutical PreparationsIBA
01/2022 - 05/2010
12InsecticidesIBA
07/2021 - 11/2004
11Immunoglobulin G (IgG)IBA
01/2022 - 01/2012
11Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)IBA
10/2021 - 05/2010
11pyrimethamine drug combination fanasil (Fansidar)FDA Link
03/2021 - 07/2002
11Proteins (Proteins, Gene)FDA Link
03/2021 - 07/2015
11VaccinesIBA
01/2020 - 04/2011
10Merozoite Surface Protein 1 (MSA1)IBA
07/2019 - 05/2009
9artenimol (dihydroartemisinin)IBA
01/2022 - 03/2015
9piperaquineIBA
01/2022 - 03/2015
7EnzymesIBA
01/2020 - 01/2009
6Indicators and Reagents (Reagents)IBA
03/2020 - 12/2007
5Ivermectin (Mectizan)FDA Link
01/2022 - 05/2013
5Hemoglobins (Hemoglobin)IBA
10/2021 - 03/2005
5Histidine (L-Histidine)FDA Link
03/2021 - 01/2016
5Lumefantrine Drug Combination Artemether (Coartem)FDA Link
01/2019 - 04/2005
5ArtesunateIBA
03/2015 - 03/2003
4Amodiaquine (Camoquin)FDA Link
03/2021 - 07/2002
4Malaria VaccinesIBA
01/2018 - 01/2012
3Complement System Proteins (Complement)IBA
02/2022 - 01/2014
3Biological ProductsIBA
01/2022 - 09/2007
3glucose-6-phosphate dehydrogenase A-IBA
01/2021 - 05/2010
3ImmunosorbentsIBA
01/2020 - 01/2009
3Salivary Proteins and PeptidesIBA
10/2019 - 01/2012
3Chloroquine (Aralen)FDA LinkGeneric
01/2017 - 04/2003
3Pyrethrins (Pyrethroids)FDA Link
11/2016 - 09/2007
2Oxidoreductases (Dehydrogenase)IBA
01/2021 - 08/2015
21- acetyl- 1,2,3,3a,8,8a- hexahydro- 8a- hydroxy- 5- methoxypyrrolo(2,3- b)indole (CHMI)IBA
10/2020 - 01/2018
2GlobinsIBA
11/2017 - 07/2014
2DNA (Deoxyribonucleic Acid)IBA
01/2017 - 08/2013
2Membrane Proteins (Integral Membrane Proteins)IBA
01/2017 - 04/2015
2Sulfadoxine (Sulformethoxine)FDA Link
01/2009 - 04/2003
2Pyrimethamine (Daraprim)FDA Link
04/2005 - 04/2003
1N-methylchlorphentermineIBA
01/2022
1tafenoquineIBA
01/2022
1artesunate drug combination pyronaridine tetraphosphateIBA
01/2022
118S Ribosomal RNAIBA
01/2021
1NucleotidesIBA
01/2021
1Immunoglobulin IsotypesIBA
01/2021
1BuffersIBA
11/2020
1Cytochrome P-450 CYP2D6 (CYP2D6)IBA
10/2019
13-O-(methylthiomethyl)apiitol tetraacetateIBA
08/2019
1ElementsIBA
01/2019
1Immune Sera (Antisera)IBA
01/2019
1methyl 1- ribofuranosyl- 1,2,4- triazole- 3- carboxamidateIBA
01/2018
1L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
01/2018
1HaptoglobinsIBA
01/2018
1Sickle HemoglobinIBA
11/2017
1ORALIT (ORS)IBA
10/2017
1Blood Group Antigens (Blood Groups)IBA
01/2017
1(2,3,5,6- tetrafluoro- 4- methoxymethylphenyl)methyl- 2,2- dimethyl- 3- (1- propenyl)cyclopropanecarboxylateIBA
01/2017
1RNA (Ribonucleic Acid)IBA
12/2016
1Nucleic AcidsIBA
12/2015
1Phosphates (Orthophosphate)IBA
08/2015
1Recombinant ProteinsIBA
07/2015
1Methylene Blue (Methylthioninium Chloride)FDA Link
03/2015
1Azithromycin (Zithromax)FDA LinkGeneric
02/2015
1Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric
01/2015
1Genetic Markers (Genetic Marker)IBA
07/2014
11,4-thiomorpholine-3,5-dicarboxylic acidIBA
07/2013
1Drug CombinationsIBA
08/2011
1ArtemisininsIBA
05/2010

Therapy/Procedure

16Mass Drug Administration
02/2022 - 03/2003
15Therapeutics
01/2022 - 09/2006
5Aftercare (After-Treatment)
01/2022 - 10/2007
3Chemoprevention
03/2021 - 01/2018
2Insecticide-Treated Bednets
01/2020 - 03/2005
1Treatment Delay
10/2020
1Blood Transfusion (Blood Transfusions)
01/2017
1Drug Therapy (Chemotherapy)
01/2017
1Mosquito Nets
01/2017